Fluoride & the Brain

“Yes, your government knowingly adds this to our drinking water and other products like toothpaste. But just assume that they are looking out for you and that they are not criminal puppets working for the globalist control freaks. Don’t worry you are not under their control, you are a very free person living in a town called Ignorance from a country called Bliss.”

Key Findings – Fluoride & the Brain: (Click for more detail)

1) Fluoride’s ability to damage the brain represents one of the most active areas of research on fluoride toxicity today.

2) The research on fluoride and the brain has been fueled by 18 human studies from China, India, Iran, and Mexico finding elevated levels of fluoride exposure to be associated with IQ deficits in children. Fluoride’s impact on IQ is exacerbated among children with low-iodine exposure.

3) The impact of fluoride on children’s IQ has been documented even after controlling for children’s lead exposure, iodine exposure, parental education and income status, and other known factors that might impact the results (Rocha-Amador 2007; Xiang 2003 a,b).

4) In addition to IQ studies, 3 studies (Yu 1996; Du 1992; Han 1989) have found that fluoride accumulates in the brain of the fetus, causing damage to cells and neurotransmitters and 1 study (Li 2004) has found a correlation between exposure to fluoride during fetal development and behavioral deficits among neonates.

5) Several recent studies have found that even adult exposures to fluoride may result in central nervous system disturbances, particularly among industrial workers.

5) The findings of neurological effects in fluoride-exposed humans is consistent with, and strengthened by, recent findings from over 40 animal studies published since 1992. As with the studies on humans, the studies on animals have reported an impairment in learning and memory prorcesses among the fluoride-treated groups.

6) The animal studies have also documented considerable evidence of direct toxic effects of fluoride on brain tissue, even at levels as low as 1 ppm fluoride in water (Varner 1998). These effects include:

— reduction in nicotinic acetylcholine receptors;
— reduction in lipid content;
— impaired anti-oxidant defense systems;
— damage to the hippocampus;
— damage to the purkinje cells; 
— increased uptake of aluminum; 
— formation of beta-amyloid plaques (the classic brain abnormality in Alzheimer’s disease); 
— exacerbation of lesions induced by iodine deficiency; and 
— accumulation of fluoride in the pineal gland.

Articles of Interest – Fluoride & the Brain: (back to top)

Available Full-Text Papers Online – Fluoride & the Brain: (back to top)

FULL-TEXT (pdf): Xiang Q, et al. (2003). Effect of fluoride in drinking water on children’s intelligence. Fluoride 36: 84-94.

FULL-TEXT (pdf): Lu Y, et al (2000). Effect of high-fluoride water on intelligence of children. Fluoride 33:74-78.

FULL-TEXT (pdf): Varner JA, et al. (1998). Chronic administration of aluminum-fluoride and sodium-fluoride to rats in drinking water: alterations in neuronal and cerebrovascular integrity. Brain Research 784: 284-298.

FULL-TEXT (pdf): Mullenix P, et al. (1995).Neurotoxicity of sodium fluoride in rats. Neurotoxicology and Teratology 17:169-177.

FULL-TEXT (html): Lin Fa-Fu; et al (1991). The relationship of a low-iodine and high-fluoride environment to subclinical cretinism in Xinjiang. Iodine Deficiency Disorder Newsletter Vol. 7. No. 3. (August).

NOTABLE QUOTES– Fluoride’s Impact on the Brain: (back to top)

“it is apparent that fluorides have the ability to interfere with the functions of the brain.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA’s Standards. National Academies Press, Washington D.C. p 187.

“Studies in animals and human populations suggest that fluoride exposure, at levels that are experienced by a significant proportion of the population whose drinking water is fluoridated, may have adverse impacts on the developing brain. Though no final conclusions may be reached from available data, the findings are provocative and of significant public health concern.”
SOURCE: Schettler T, et al. (2000). Known and suspected developmental neurotoxicants. pp. 90-92. In: 
In Harms Way – Toxic Threats to Child Development. Greater Boston Physicians for Social Responsibility: Cambridge, MA. (See report)

“Fluorides also increase the production of free radicals in the brain through several different biological pathways. These changes have a bearing on the possibility that fluorides act to increase the risk of developing Alzheimer’s disease.” 
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA’s Standards. National Academies Press, Washington D.C. p 186.

“Studies of populations exposed to different concentrations of fluoride should be undertaken to evaluate neurochemical changes that may be associated with dementia.Consideration should be given to assessing effects from chronic exposure, effects that might be delayed or occur late-in-life, and individual susceptibility.” 
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA’s StandardsNational Academies Press, Washington D.C. p 187.

HUMAN STUDIES– Fluoride’s Impact on IQ: (back to top)

“We found that exposure to fluoride (F) in urine was associated with reduced Performance, Verbal, and Full IQ scores before and after adjusting for confounders. The same pattern was observed for models with F in water as the exposure variable…. The individual effect of F in urine indicated that for each mg increase of F in urine a decrease of 1.7 points in Full IQ might be expected.”
SOURCE: Rocha-Amador D, et al. (2007). Decreased intelligence in children and exposure to fluoride and arsenic in drinking water. 
Cadernos de Saude Publica 23(Suppl 4):S579-87.

“These negative correlations between IQ and urinary As and between IQ and urinary fluoride indicate that exposure to high levels of As or fluoride, or both, could affect children’s intelligence… This study indicates that exposure to fluoride in drinking water is associated with neurotoxic effects in children.”
SOURCE: Wang SX, et al. (2007). Arsenic and fluoride exposure in drinking water: children’s IQ and growth in Shanyin county, Shanxi province, China. 
Environmental Health Perspectives 115(4):643-7.

“In agreement with other studies elsewhere, these findings indicate that children drinking high F water are at risk for impaired development of intelligence.”
SOURCE: Trivedi MH, et al. (2007). Effect of high fluoride water on intelligence of school children in India. 
Fluoride 40(3):178-183.

“Based on the findings of this study, exposure of children to high levels of fluoride may carry the risk of impaired development of intelligence.”
SOURCE: Seraj B, et al. (2006). [Effect of high fluoride concentration in drinking water on children’s intelligence]. 
Journal of Dental Medicine 19(2):80-86.

“A few epidemiologic studies of Chinese populations have reported IQ deficits in children exposed to fluoride at 2.5 to 4 mg/L in drinking water. Although the studies lacked sufficient detail for the committee to fully assess their quality and relevance to U.S. populations, the consistency of the results appears significant enough to warrant additional research on the effects of fluoride on intelligence.”
SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA’s Standards. National Academies Press, Washington D.C. p. 6.

“Conclusion: High fluoride burden has a definite effect on the intellectual and physical development of children.”
SOURCE: Wang S, et al. (2005). Effects of coal burning related endemic fluorosis on body development and intelligence levels of children. Journal of Applied Clinical Pediatrics 20(9): 897-898.

“In our study, it was shown that the average IQ of children in a fluoride endemic area was somewhat lower than the control, but the result was not significant (P>0.05). The rate of children with “low” IQs, however, was elevated as compared to the control, and this was very statistically significant… Our study showed that, within the fluoride endemic area, the average IQ of children suffering from dental fluorosis is clearly lower than those that show no signs of the disease, and this result is very significant (P <0.01). This IQ difference of 8.12 suggests that children suffering from dental fluorosis might be particularly sensitive to excess fluoride, and that the manifestation of this is not limited to the typical symptoms of fluorosis, but, more seriously, also disrupts intellectual development.”
SOURCE: Li Y, et al. (2003). The effects of endemic fluoride poisoning on the intellectual development of children in Baotou. 
Chinese Journal of Public Health Management19(4):337-338.




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